| Primary Identifier | MGI:2443787 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 320311 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable small GTPase binding activity and ubiquitin protein ligase activity. Involved in cellular response to amino acid starvation; negative regulation of TORC1 signaling; and positive regulation of autophagy. Predicted to be located in lysosome and organelle membrane. Predicted to be active in lysosomal membrane. Is expressed in forebrain. Orthologous to human RNF152 (ring finger protein 152). PHENOTYPE: Mice homozygous for a null mutation display reduced starvation induced autophagy in MEFs. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
