Primary Identifier | MGI:2442544 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 226414 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable RNA binding activity and aspartate-tRNA ligase activity. Predicted to be involved in aspartyl-tRNA aminoacylation. Located in cytoplasm and synapse. Part of aminoacyl-tRNA synthetase multienzyme complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human DARS1 (aspartyl-tRNA synthetase 1). PHENOTYPE: Mice homozygous for a knock-out allele die between E11 and E14. Mice heterozygous for the allele exhibit decreased PPI. [provided by MGI curators] |