Primary Identifier | MGI:1927803 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 64435 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables IgA binding activity; IgM binding activity; and transmembrane signaling receptor activity. Predicted to be involved in signal transduction. Predicted to act upstream of or within immune response. Predicted to be active in plasma membrane. Is expressed in brain; cerebellum; and spinal cord. Orthologous to human FCAMR (Fc alpha and mu receptor). PHENOTYPE: Homozygous null mice have enhanced germinal center formation, affinity maturation and memory induction of IgG3 producing B cells after immunization with T cell-independent antigens. [provided by MGI curators] |