| Primary Identifier | MGI:2442295 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 226421 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable GTP binding activity and GTPase activity. Involved in negative regulation of toll-like receptor 4 signaling pathway and negative regulation of toll-like receptor 9 signaling pathway. Acts upstream of or within cellular response to type II interferon. Located in late endosome; lysosome; and phagocytic vesicle. Orthologous to human RAB7B (RAB7B, member RAS oncogene family). PHENOTYPE: Mice homozygous for a null allele exhibit impaired dendritic cell migration with reduced number of small lysosomes per cell in LPS-exposed cells. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
