Primary Identifier | MGI:3828086 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 667118 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and transcription cis-regulatory region binding activity. Involved in negative regulation of muscle cell differentiation; negative regulation of transcription by RNA polymerase II; and regulation of insulin secretion involved in cellular response to glucose stimulus. Acts upstream of or within blastocyst hatching. Located in cytoplasm and nucleolus. Is expressed in early conceptus; nervous system; neural retina; and secondary oocyte. Orthologous to human ZBED6 (zinc finger BED-type containing 6). PHENOTYPE: Mice homozygous for a null allele display sex specific increases in body, skeletal muscle, and organ sizes. [provided by MGI curators] |