| Primary Identifier | MGI:1919924 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 72674 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables adiponectin binding activity; identical protein binding activity; and signaling receptor activity. Involved in glucose homeostasis; positive regulation of cold-induced thermogenesis; and regulation of primary metabolic process. Acts upstream of or within adiponectin-activated signaling pathway. Located in plasma membrane. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; eye; and genitourinary system. Human ortholog(s) of this gene implicated in breast cancer; macular degeneration; and prostate adenocarcinoma. Orthologous to human ADIPOR1 (adiponectin receptor 1). PHENOTYPE: Mice homozygous for a targeted allele exhibit abnormal homeostasis, adipose tissue morphology and adaptive thermogenesis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
