| Primary Identifier | MGI:109234 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 16565 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Involved in regulation of postsynaptic membrane neurotransmitter receptor levels and retrograde dendritic transport. Acts upstream of or within corpus callosum development. Is active in glutamatergic synapse and postsynaptic endosome. Is expressed in central nervous system; dorsal root ganglion; and neural retina. Orthologous to human KIF21B (kinesin family member 21B). PHENOTYPE: Homozygous KO reduces dendrite branching and spine density as a result of reduced microtubule growth, resulting in impaired spatial learning and cued conditioning behavior. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
