Primary Identifier | MGI:3029290 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 226442 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in embryonic body morphogenesis and stem cell differentiation. Predicted to be located in nucleoplasm. Is expressed in several structures, including branchial arch; egg cylinder; genitourinary system; immune system; and intestine. Orthologous to human ZNF281 (zinc finger protein 281). PHENOTYPE: Mice homozygous for a knock-out allele exhibit embryonic lethality between E7.5 and E8.5. [provided by MGI curators] |