| Primary Identifier | MGI:1098271 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 19735 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables adenylate cyclase inhibitor activity. Involved in several processes, including regulation of G protein-coupled receptor signaling pathway; regulation of muscle system process; and relaxation of cardiac muscle. Acts upstream of or within brown fat cell differentiation. Located in cytoplasmic side of plasma membrane and cytosol. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and immune system. Orthologous to human RGS2 (regulator of G protein signaling 2). PHENOTYPE: Heterozygous and homozygous mice for one allele display equivalent levels of blood pressure elevation, renovascular defects, persistent constriction of the resistance vasculature, and prolonged response of the vasculature to vasoconstrictors in vivo. Mice homozygous for another allele appear normal. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
