| Primary Identifier | MGI:1347046 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 26374 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in several processes, including negative regulation of fatty acid biosynthetic process; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; and response to ionizing radiation. Predicted to be located in Golgi membrane. Predicted to be part of Cul4A-RING E3 ubiquitin ligase complex. Is expressed in central nervous system; genitourinary system; limb; and liver. Orthologous to human COP1 (COP1 E3 ubiquitin ligase). PHENOTYPE: Mice homozygous for a conditional allele activated in prostate epithelial cells exhibit prostate gland hyperplasia and prostate intraepithelial neoplasia due to increased cell proliferation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
