Primary Identifier | MGI:3618742 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 723821 |
Mgi Type | miRNA gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including cellular response to forskolin; cellular response to leukemia inhibitory factor; and negative regulation of fatty acid oxidation. Is expressed in several structures, including arterial system; cranium; embryo mesenchyme; extracellular matrix; and heart and pericardium. Used to study Rett syndrome. Orthologous to human MIR199A2 (microRNA 199a-2). PHENOTYPE: Null mice exhibit premature death, decreased body and brains size, behavioral and breathing abnormalities, and neurons with smaller cell body and nucleus. [provided by MGI curators] |