Primary Identifier | MGI:1858730 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 53330 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within Golgi to plasma membrane protein transport; cellular response to type II interferon; and regulation of Golgi to plasma membrane protein transport. Located in phagocytic vesicle and trans-Golgi network. Part of SNARE complex. Is active in presynaptic endosome membrane. Is expressed in cerebellum layer; gonad; and ventral tegmental area. Orthologous to human VAMP4 (vesicle associated membrane protein 4). PHENOTYPE: Mice homozygous for a null allele display increased insulin in pancreas beta cells and improved glucose tolerance. [provided by MGI curators] |