| Primary Identifier | MGI:88050 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 11807 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables high-density lipoprotein particle binding activity. Acts upstream of or within several processes, including cholesterol homeostasis; negative regulation of lipase activity; and regulation of intestinal cholesterol absorption. Located in extracellular space. Is expressed in several structures, including alimentary system; liver; and lung. Orthologous to human APOA2 (apolipoprotein A2). PHENOTYPE: Homozygous null mutation of this gene results in a reduction of total cholesterol, HDL cholesterol, free fatty acids, insulin, and glucose levels in both the fasted and unfasted states. Strain specific alleles have been associated with varying degrees of amyloidosis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
