Primary Identifier | MGI:1333874 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 21945 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA binding activity. Acts upstream of or within decidualization; extrinsic apoptotic signaling pathway via death domain receptors; and negative regulation of macromolecule metabolic process. Located in cytoplasm and nucleolus. Is expressed in central nervous system and retina. Orthologous to human DEDD (death effector domain containing). PHENOTYPE: Mice homozygous for a null allele display reduced body size, organ size and organ weight without reductions in cell numbers. [provided by MGI curators] |