|  Help  |  About  |  Contact Us

Protein Coding Gene : Nit1 nitrilase 1

Primary Identifier  MGI:1350916 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  27045
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables deaminated glutathione amidase activity. Involved in amide catabolic process. Located in mitochondrion. Is expressed in several structures, including colon; gonad; mammary gland; musculature; and spleen. Orthologous to human NIT1 (nitrilase 1).
PHENOTYPE: Mice that are either heterozygous or homozygous for a knock-out allele exhibit increased incidence of N-nitrosomethylbenzylamine (NMBA)-induced tumors in the forestomach (papillomas and dysplasias). [provided by MGI curators]
  • synonyms:
  • expressed sequence tag mouse EST 30,
  • MGI:1334466,
  • Nit1,
  • MGI:2138182,
  • ESTM30,
  • W57327,
  • EST W57327,
  • AI255805,
  • nitrilase 1,
  • expressed sequence AI255805

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For