Primary Identifier | MGI:1350916 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 27045 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables deaminated glutathione amidase activity. Involved in amide catabolic process. Located in mitochondrion. Is expressed in several structures, including colon; gonad; mammary gland; musculature; and spleen. Orthologous to human NIT1 (nitrilase 1). PHENOTYPE: Mice that are either heterozygous or homozygous for a knock-out allele exhibit increased incidence of N-nitrosomethylbenzylamine (NMBA)-induced tumors in the forestomach (papillomas and dysplasias). [provided by MGI curators] |