Primary Identifier | MGI:1276111 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 18637 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable amyloid-beta binding activity; protein folding chaperone; and unfolded protein binding activity. Acts upstream of or within protein folding. Predicted to be located in cytosol; mitochondrion; and nucleus. Predicted to be part of RPAP3/R2TP/prefoldin-like complex and prefoldin complex. Predicted to be active in cytoplasm. Orthologous to human PFDN2 (prefoldin subunit 2). PHENOTYPE: Mice homozygous for a transgenic gene disruption exhibit embryonic lethality at E6. [provided by MGI curators] |