Primary Identifier | MGI:1336885 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 12523 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity. Involved in regulation of gene expression; regulation of macrophage activation; and regulation of signal transduction. Predicted to be located in intracellular membrane-bounded organelle and plasma membrane. Predicted to be active in external side of plasma membrane. Is expressed in brain; embryo; and testis. Orthologous to human CD84 (CD84 molecule). PHENOTYPE: Mice homozygous for a knock-out allele of this gene show defects in T follicular helper function and germinal center formation. Mice homozygous for a different knock-out allele display normal platelet physiology and thrombus formation. [provided by MGI curators] |