| Primary Identifier | MGI:98229 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 20219 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including complement component C1q complex binding activity; identical protein binding activity; and virion binding activity. Predicted to be involved in several processes, including modulation by host of viral process; negative regulation of exo-alpha-sialidase activity; and negative regulation of monocyte differentiation. Predicted to be part of protein-containing complex. Predicted to be active in extracellular space. Is expressed in liver. Human ortholog(s) of this gene implicated in amyloidosis. Orthologous to human APCS (amyloid P component, serum). PHENOTYPE: Mice homozygous for a null allele exhibit decreased antibody productions, increased autoimmune antibodies, reduced amyloidosis and glomerulonephrosis depending on strain background. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
