| Primary Identifier | MGI:96429 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 15951 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables double-stranded DNA binding activity and transcription coregulator activity. Involved in cellular response to interferon-alpha. Acts upstream of or within several processes, including cellular response to interferon-beta; positive regulation of osteoblast differentiation; and regulation of transcription by RNA polymerase II. Located in nuclear inclusion body and nucleolus. Is expressed in esophagus; male reproductive gland or organ; and tibia. Orthologous to several human genes including IFI16 (interferon gamma inducible protein 16). PHENOTYPE: Homozygous null mice show decreased susceptibility to LPS-induced shock, showing decreased secretion and serum levels of pro-inflammatory cytokines. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
