| Primary Identifier | MGI:1859252 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 54418 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable actin binding activity. Involved in several processes, including cytoskeleton organization; meiotic nuclear division; and oogenesis. Acts upstream of or within actin filament bundle assembly and meiotic chromosome movement towards spindle pole. Located in several cellular components, including endoplasmic reticulum membrane; microvillus; and spindle. Is expressed in several structures, including brain; ganglia; neural ectoderm; otocyst; and testis. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 47. Orthologous to human FMN2 (formin 2). PHENOTYPE: Female mice homozygous for a knock-out allele display polyploid embryo formation, recurrent pregnancy loss, hypofertility, and inadequate nursing behavior. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
