| Primary Identifier | MGI:2443573 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 320202 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cytokine activity. Predicted to be involved in anterior/posterior axis specification. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including compacted morula; embryo ectoderm; embryo mesoderm; gonad; and primitive streak. Human ortholog(s) of this gene implicated in congenital heart disease. Orthologous to human LEFTY2 (left-right determination factor 2). PHENOTYPE: Mice homozygous for one null allele exhibit embryonic lethality, defects in axial patterning, absent notochord, somites, head folds and heart, and defects yolk sac development. Mice homozygous for another allele exhibit postnatal lethality and left isomerism. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
