Primary Identifier | MGI:1914497 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 67247 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable molybdenum ion binding activity; molybdopterin cofactor binding activity; and oxidoreductase activity, acting on other nitrogenous compounds as donors. Predicted to be involved in cellular detoxification of nitrogen compound; nitrate metabolic process; and nitric oxide biosynthetic process. Located in mitochondrion. Is expressed in cerebral cortex ventricular layer. Orthologous to human MTARC2 (mitochondrial amidoxime reducing component 2). PHENOTYPE: Mice homozygous for null allele exhibit rapidly progressive hind limb paralysis at 7-10 weeks of age and young females have decreased weight and body fat mass. [provided by MGI curators] |