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Protein Coding Gene : Nenf neuron derived neurotrophic factor

Primary Identifier  MGI:1913458 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  66208
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables growth factor activity. Involved in negative regulation of appetite. Acts upstream of or within positive regulation of MAPK cascade. Located in endoplasmic reticulum; extracellular space; and mitochondrion. Is expressed in brain; heart; lung; metanephros; and spinal cord. Orthologous to human NENF (neudesin neurotrophic factor).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased anxiety-related response, abnormal dendrite morphology and decreased dopamine levels. [provided by MGI curators]
  • synonyms:
  • neudesin,
  • Nenf,
  • 1110060M21Rik,
  • RIKEN cDNA 1110060M21 gene,
  • neuron derived neurotrophic factor

Features --> Cross References

Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

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Disease

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