Primary Identifier | MGI:1913458 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 66208 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables growth factor activity. Involved in negative regulation of appetite. Acts upstream of or within positive regulation of MAPK cascade. Located in endoplasmic reticulum; extracellular space; and mitochondrion. Is expressed in brain; heart; lung; metanephros; and spinal cord. Orthologous to human NENF (neudesin neurotrophic factor). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased anxiety-related response, abnormal dendrite morphology and decreased dopamine levels. [provided by MGI curators] |