Primary Identifier | MGI:1915882 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 68632 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within hematopoietic stem cell homeostasis. Predicted to be located in nuclear body. Predicted to be active in nucleoplasm. Is expressed in genitourinary system. Orthologous to human MYCT1 (MYC target 1). PHENOTYPE: Mice homozygous for a null allele exhibit restricted tumor progression in various tumor models, showing reduced angiogenesis to tumors, enhanced high endothelial venule formation, and an antitumor immune microenvironment. [provided by MGI curators] |