| Primary Identifier | MGI:1344353 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 23924 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ATP hydrolysis activity and dynein complex binding activity. Acts upstream of or within microtubule cytoskeleton organization; neuron migration; and protein localization. Located in several cellular components, including axon; centrosome; and lipid droplet. Is expressed in several structures, including brain; genitourinary system; intestine; liver; and spleen. Orthologous to human KATNA1 (katanin catalytic subunit A1). PHENOTYPE: Mice homozygous for a null allele exhibit complete prenatal lethality. Heterozygous null mice exhibit altered neuronal progenitor proliferation in the developing cortex and during adult hippocampal neurogenesis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
