| Primary Identifier | MGI:1926058 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 78808 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables syntaxin-1 binding activity. Involved in positive regulation of exocytosis; regulation of synaptic vesicle exocytosis; and regulation of synaptic vesicle priming. Acts upstream of or within exocytosis and regulation of exocytosis. Part of acetylcholine-gated channel complex. Is active in hippocampal mossy fiber to CA3 synapse and presynapse. Is extrinsic component of neuronal dense core vesicle membrane. Orthologous to human STXBP5 (syntaxin binding protein 5). PHENOTYPE: Mice homozygous for a null allele exhibit some background sensitive prenatal lethality and increased synaptic transmission. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
