| Primary Identifier | MGI:1916151 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 215798 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables laminin binding activity. Involved in several processes, including adenylate cyclase-activating G protein-coupled receptor signaling pathway; heart trabecula formation; and myelination in peripheral nervous system. Predicted to be located in cell surface and cytoplasm. Predicted to be active in plasma membrane. Is expressed in several structures, including embryo mesenchyme; heart; musculoskeletal system; urinary system; and vascular system. Used to study idiopathic scoliosis. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome. Orthologous to human ADGRG6 (adhesion G protein-coupled receptor G6). PHENOTYPE: Mice homozygous for a null mutation die during organogenesis and display signs of circulatory failure. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
