| Primary Identifier | MGI:1100525 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 18101 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable neuropeptide receptor activity. Involved in several processes, including antiviral innate immune response; negative regulation of interleukin-6 production; and positive regulation of osteoclast proliferation. Predicted to be located in cytosol. Predicted to be active in plasma membrane. Is expressed in brain; dentate gyrus subgranular zone; lung; lung epithelium; and lung mesenchyme. Orthologous to human NMBR (neuromedin B receptor). PHENOTYPE: Mice homozygous for a knock-out allele show a 50% reduction in the thermoregulatory response to neuromedin B as well as impaired maternal behavior in response to restraint-induced stress. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
