Primary Identifier | MGI:3610311 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 268291 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be located in membrane. Predicted to be part of ubiquitin ligase complex. Predicted to be active in cytoplasm. Is expressed in adrenal gland; cerebral cortex intermediate zone; cerebral cortex mantle layer; cerebral cortex ventricular layer; and vertebral axis musculature. Orthologous to human RNF217 (ring finger protein 217). PHENOTYPE: Macrophage- and intestinal enterocyte-specific knock-out mice show abnormal iron metabolism. [provided by MGI curators] |