Primary Identifier | MGI:2685581 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 327743 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable heparin binding activity and integrin binding activity. Predicted to be involved in several processes, including positive regulation of cell differentiation; regulation of mitochondrial membrane potential; and regulation of reactive oxygen species biosynthetic process. Predicted to act upstream of or within negative regulation of angiogenesis and negative regulation of cell population proliferation. Predicted to be located in mitochondrion. Predicted to be active in extracellular matrix and extracellular space. Is expressed in embryo. Used to study breast metaplastic carcinoma and progressive pseudorheumatoid arthropathy of childhood. Human ortholog(s) of this gene implicated in arthropathy and progressive pseudorheumatoid arthropathy of childhood. Orthologous to human CCN6 (cellular communication network factor 6). PHENOTYPE: Homozygous null mice are viable and fertile with no obvious abnormalities in size, weight, skeletal development, ossification, or the occurrence of joint disease. [provided by MGI curators] |