| Primary Identifier | MGI:1924427 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 109205 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables SUMO polymer binding activity. Involved in cochlea development. Acts upstream of or within inner ear morphogenesis; locomotory behavior; and sensory perception of sound. Located in nucleus. Is expressed in several structures, including brain; cranial ganglion; genitourinary system; immune system; and inner ear. Orthologous to human SOBP (sine oculis binding protein homolog). PHENOTYPE: Homozygous mutant mice exhibit open-field hyperactivity and circling behavior from weaning. Their hearing thresholds are elevated at all frequencies; the hearing impairment does not progress over time. [provided by MGI curators] |