| Primary Identifier | MGI:1918817 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 71567 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables chromatin binding activity. Involved in DNA repair and female gamete generation. Part of MCM8-MCM9 complex. Is expressed in several structures, including brain; genitourinary system; liver; neural retina; and spleen. Used to study hepatocellular carcinoma. Human ortholog(s) of this gene implicated in ovarian dysgenesis 4. Orthologous to human MCM9 (minichromosome maintenance 9 homologous recombination repair factor). PHENOTYPE: Mice homozygous for gene trap alleles display germ cell loss with reduced fertility or infertility and increased tumor incidence, particulary of hepatocellular carcinomas. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
