Primary Identifier | MGI:101937 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 18768 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables cAMP-dependent protein kinase inhibitor activity. Acts upstream of or within negative regulation of cAMP-dependent protein kinase activity. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including brain; femur; genitourinary system; gut; and integumental system. Orthologous to human PKIB (cAMP-dependent protein kinase inhibitor beta). PHENOTYPE: Homozygotes for a targeted null mutation exhibit reduced protein kinase inhibitor activity in the testis but are phenotypically normal and fertile. [provided by MGI curators] |