| Primary Identifier | MGI:2684909 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 216021 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including inner ear development; positive regulation of otic vesicle morphogenesis; and positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Located in cell cortex and nucleus. Human ortholog(s) of this gene implicated in pre-eclampsia. Orthologous to human STOX1 (storkhead box 1). PHENOTYPE: Homozygous null pregnant mice develop gestational hypertension with placental vascular and extracellular matrix abnormalities and some placental hypoxia. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
