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Protein Coding Gene : Mrln myoregulin

Primary Identifier  MGI:1916813 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  69563
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables enzyme inhibitor activity. Acts upstream of or within negative regulation of ATPase-coupled calcium transmembrane transporter activity; negative regulation of calcium ion import into sarcoplasmic reticulum; and response to wounding. Located in sarcoplasmic reticulum membrane. Is expressed in several structures, including diaphragm; heart; leg muscle; somite; and tongue. Orthologous to human MRLN (myoregulin).
PHENOTYPE: Mice homozygous for a knock-out allele show improved exercise performance and enhanced Ca2+ handling in skeletal muscle. Mice homozygous for another knock-out exhibit reduced myofiber numbers and muscle regeneration. [provided by MGI curators]
  • synonyms:
  • Mrln,
  • 2310015B20Rik,
  • Linc-RAM,
  • myoregulin,
  • RIKEN cDNA 2310015B20 gene,
  • MLN

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For