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Protein Coding Gene : Ggt5 gamma-glutamyltransferase 5
Primary Identifier  MGI:1346063 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  23887
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables leukotriene-C(4) hydrolase. Acts upstream of or within inflammatory response and leukotriene D4 biosynthetic process. Located in plasma membrane. Orthologous to human GGT5 (gamma-glutamyltransferase 5).
PHENOTYPE: Homozygous mutants show an attenuation in neutrophil recruitment in an experimental model of peritonitis. [provided by MGI curators]
  • synonyms:
  • gamma-glutamyltransferase 5,
  • GGT-REL,
  • Ggt5,
  • GGL,
  • gamma-glutamyl leukotrienase,
  • MGI:2143643,
  • expressed sequence AI551243,
  • AI551243,
  • Ggtla1,
  • gamma-glutamyltransferase-like activity 1
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2 Involved In Mutations

Trail: ProteinCodingGene

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

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Interactions

12 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

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