Primary Identifier | MGI:1338756 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 21830 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within spermatogenesis. Predicted to be located in cytoplasm. Is expressed in large intestine; metanephros; ovary; submandibular gland; and testis. Orthologous to human SPMAP2 (sperm microtubule associated protein 2). PHENOTYPE: Males homozygotes for a transgenic insertional mutation are sterile due to a block in spermiogenesis. Testis weights are reduced, and mutants exhibit multiple abnormalities in elongated spermatids in the seminiferous tubule lumen. [provided by MGI curators] |