Primary Identifier | MGI:2150393 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 170483 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Contributes to calcium channel activity. Involved in protein insertion into membrane and regulation of calcium ion transport. Located in neuronal cell body. Part of NMDA selective glutamate receptor complex. Is expressed in central nervous system; gut gland; retina; and testis. Orthologous to human GRIN3B (glutamate ionotropic receptor NMDA type subunit 3B). PHENOTYPE: Mice homozygous for a null allele show a mild impairment in motor learning or coordination, reduced home cage activity, a highly increased social interaction with familiar cagemates in their home cage but moderately increased anxiety-like behavior and reduced social interaction in a new environment. [provided by MGI curators] |