Primary Identifier | MGI:1891409 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 246086 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within regulation of transcription by RNA polymerase II. Part of transcription regulator complex. Is expressed in gut; nervous system; sensory organ; testis; and urinary system. Orthologous to human ONECUT3 (one cut homeobox 3). PHENOTYPE: Mice homozygous for a reporter/null allele display normal pancreas and gut development with no apparent alterations in enteroendocrine differentiation. [provided by MGI curators] |