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Protein Coding Gene : Abhd17a abhydrolase domain containing 17A
Primary Identifier  MGI:106388 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  216169
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable palmitoyl-(protein) hydrolase activity. Predicted to be involved in several processes, including negative regulation of NLRP3 inflammasome complex assembly; protein depalmitoylation; and regulation of protein localization. Predicted to be located in nuclear speck; postsynaptic density; and recycling endosome membrane. Predicted to be active in glutamatergic synapse; postsynaptic density membrane; and postsynaptic recycling endosome membrane. Orthologous to human ABHD17A (abhydrolase domain containing 17A, depalmitoylase).
PHENOTYPE: Mice homozygous for a null mutation display improved glucose tolerance. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 1700013O15 gene,
  • MGI:2384913,
  • abhydrolase domain containing 17A,
  • 1700013O15Rik,
  • MGD-MRK-34081,
  • D10Bwg1364e,
  • MGC:11699,
  • cDNA sequence BC005632,
  • Fam108a,
  • Abhd17a,
  • DNA segment, Chr 10, Brigham & Women's Genetics 1364 expressed,
  • BC005632,
  • family with sequence similarity 108, member A,
  • MGI:1923653
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