| Primary Identifier | MGI:1920014 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 103236 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in endocytosis; positive regulation of canonical Wnt signaling pathway; and signal transduction. Predicted to be located in cell cortex. Predicted to be active in cytoplasm; nucleus; and plasma membrane. Is expressed in brain; genitourinary system; and skin. Orthologous to human CSNK1G2 (casein kinase 1 gamma 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit accelerated TNF-induced lethality and enhanced cell death in response to various necroptosis-inducing agents. Males exhibit an enhanced necroptosis response and premature reproductive system aging. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
