| Primary Identifier | MGI:1920468 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 73218 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable aspartic endopeptidase activity, intramembrane cleaving and protein homodimerization activity. Predicted to be involved in membrane protein ectodomain proteolysis; membrane protein intracellular domain proteolysis; and regulation of immune response. Predicted to be located in several cellular components, including cytoskeleton; endosome membrane; and nucleoplasm. Predicted to be active in bounding membrane of organelle and endoplasmic reticulum membrane. Is expressed in embryo. Orthologous to human SPPL2B (signal peptide peptidase like 2B). PHENOTYPE: Mice homozygous for a gene trapped allele are viable and overtly normal with no apparent defects in B cell and dendritic cell homeostasis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
