Primary Identifier | MGI:95787 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 14708 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable G-protein beta-subunit binding activity. Involved in regulation of adenylate cyclase activity. Acts upstream of or within behavioral fear response; locomotory behavior; and receptor guanylyl cyclase signaling pathway. Is active in synapse. Is expressed in central nervous system; early conceptus; oocyte; and retina. Orthologous to human GNG7 (G protein subunit gamma 7). PHENOTYPE: Mice homozygous for a knock-out allele exhibit an enhanced startle response, loss of dopamine- and forskolin-stimulated adenylyl cyclase activity in the striatum, and increased mean insulin levels in males. [provided by MGI curators] |