Primary Identifier | MGI:3698433 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 544717 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in mitochondrial respiratory chain complex III assembly. Located in mitochondrion. Is expressed in cerebral cortex. Orthologous to human UQCC6 (ubiquinol-cytochrome c reductase complex assembly factor 6). PHENOTYPE: Mice homozygous for a null allele exhibit depletion of complex II in the mitochondria with a mild increase in circulating lactate level and reduced exercise tolerance. [provided by MGI curators] |