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Protein Coding Gene : Polr3b polymerase (RNA) III (DNA directed) polypeptide B
Primary Identifier  MGI:1917678 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  70428
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable DNA-directed 5'-3' RNA polymerase activity; DNA/RNA hybrid binding activity; and zinc ion binding activity. Predicted to contribute to RNA polymerase III activity. Predicted to be involved in positive regulation of innate immune response; positive regulation of interferon-beta production; and snRNA transcription by RNA polymerase III. Predicted to be located in cytoplasm. Predicted to be part of RNA polymerase III complex. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease and hypomyelinating leukodystrophy 8. Orthologous to human POLR3B (RNA polymerase III subunit B).
  • synonyms:
  • RIKEN cDNA A330032P03 gene,
  • A330032P03Rik,
  • expressed sequence C85372,
  • polymerase (RNA) III (DNA directed) polypeptide B,
  • RIKEN cDNA 2700078H01 gene,
  • MGI:2143941,
  • 2700078H01Rik,
  • MGI:2443266,
  • Polr3b,
  • RPC2,
  • C85372
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

Trail: ProteinCodingGene

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

6 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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