Primary Identifier | MGI:2178743 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 192188 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables cargo receptor activity. Involved in hyaluronan catabolic process and receptor-mediated endocytosis. Predicted to be located in cytosol and external side of plasma membrane. Is expressed in several structures, including extraembryonic component; genitourinary system; gut; heart; and liver. Orthologous to human STAB2 (stabilin 2). PHENOTYPE: Mice homozygous for knock-out alleles exhibit no gross abnormaities. Mice homozygous for one null allele display elevated serum hyaluronic acid levels and decreased metastasis. [provided by MGI curators] |