Primary Identifier | MGI:1914704 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 67454 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be located in endoplasmic reticulum and nucleolus. Is expressed in mandible; maxilla; and rib. Orthologous to human IKBIP (IKBKB interacting protein). PHENOTYPE: Mice with macrophage specific deletion display increased cytokine levels and mortality following LPS challenge and increased sensitivity to induced colitis. [provided by MGI curators] |