| Primary Identifier | MGI:2445110 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 320150 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables palmitoyltransferase activity and signaling receptor binding activity. Involved in several processes, including peptidyl-L-cysteine S-palmitoylation; regulation of modification of synapse structure, modulating synaptic transmission; and regulation of signal transduction. Located in Golgi apparatus. Is active in glutamatergic synapse; perforant pathway to dendrate granule cell synapse; and postsynaptic Golgi apparatus. Is expressed in several structures, including early conceptus; heart; and oocyte. Used to study Huntington's disease. Orthologous to human ZDHHC17 (zinc finger DHHC-type palmitoyltransferase 17). PHENOTYPE: Mice homozygous for a knock-out allele exhibit reminiscent of Huntington disease (decreased body weight, impaired coordination, hyperactivity, increased rearing, decreased prepulse inhibition, increased stereotypic behavior, reduced striatum, and decreased brain weight). [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
