| Primary Identifier | MGI:1916536 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 69286 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables molecular adaptor activity. Involved in fusion of sperm to egg plasma membrane involved in single fertilization and protein localization involved in acrosome reaction. Acts upstream of or within binding activity of sperm to zona pellucida. Located in acrosomal vesicle and sperm head-tail coupling apparatus. Part of protein complex involved in cell-cell adhesion. Is active in outer acrosomal membrane. Orthologous to human GLIPR1L1 (GLIPR1 like 1). PHENOTYPE: Homozygous knock-out males exhibit spermatozoa with reduced ability to undergo an acrosome reaction and impaired sperm-oocyte fusion, however males show normal fertility in vivo. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
