| Primary Identifier | MGI:1330301 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 69181 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable ion binding activity and protein kinase activity. Predicted to be involved in several processes, including intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; negative regulation of calcineurin-NFAT signaling cascade; and positive regulation of glycogen biosynthetic process. Predicted to act upstream of or within apoptotic process and phosphorylation. Part of ribonucleoprotein complex. Is expressed in several structures, including brain; eye; genitourinary system; gut gland; and hemolymphoid system gland. Orthologous to human DYRK2 (dual specificity tyrosine phosphorylation regulated kinase 2). PHENOTYPE: Homozygous knockout affects ciliogenesis, which affects bone development and leads to perinatal lethality. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
